1. Dedifferentiated Acinic cell carcinoma is a highly malignant, newly recognized parotid malignancy

2. Dedifferentiated Acinic cell carcinoma of the salivary gland is an uncommon variant of Acinic cell carcinoma, characterized by the coexistence of both an usual low-grade Acinic cell carcinoma and a high-grade dedifferentiated component, as well as by an accelerated clinical course

3. Blastema is a tissue that is formed after tissue injury in such organisms and is composed of progenitor cells or dedifferentiated cells that differentiate into various cell types during regeneration

4. It is strongly believed that the cells in the Blastema originate from dedifferentiated local tissue at the amputation site; however, adult stem cells (e.g., muscle satellite cells and possibly also the periosteum and dermis) [35-39] also contribute to the formation of the Blastema, though the number of these endogenous cells may be insufficient